Is Tamoxifen Effective In Curing Breast Cancer?

Tamoxifen, known in the trade as Nolvadex, is usually prescribed by specialists in breast cancer and is taken in pill form. A patient will stay on the drug for about five years.

Often the woman’s cancer will be tested to see if it is sensitive to the amount of oestrogen in the system. If the cancer is oestrogen sensitive, tamoxifen will be given.

Because tamoxifen is such a weak estrogen, its estrogen signals don’t stimulate very much cell growth. And because it has stolen the place away from more powerful estrogen, it blocks estrogen-stimulated cancer cell growth. In this way, tamoxifen acts like an “anti-estrogen.”

Tamoxifen may also take the place of natural estrogen in the receptors of healthy breast cells. In that way it holds down growth activity, and possibly stops abnormal growth and the development of a totally new breast cancer. By blocking natural estrogen from getting to the receptors, tamoxifen is helpful in reducing the risk of breast cancer in women at high risk who have never had breast cancer. It also can help women who have already had breast cancer in one breast by lowering the risk of a new breast cancer forming in the other breast.

One study found that radiation plus tamoxifen was much better than tamoxifen alone at reducing the risk of breast cancer coming back after a lumpectomy in women with hormone-receptor-positive breast cancer. This was true even for women with very small cancers.

For pre-menopausal women, tamoxifen is the best hormonal therapy. But tamoxifen is no longer the first choice for post-menopausal women. If you’ve been on tamoxifen for two to three years and now you’re in menopause, your doctor may recommend that you switch to an aromatase inhibitor to finish your five years of hormonal therapy. However, you can still get a lot of benefit if you take tamoxifen for up to five years and then switch to an aromatase inhibitor.

Tamoxifen was first used to fight breast cancer at the Christie Hospital in Manchester, England, in 1969. It has since proved its worth as means of stopping the spread or recurrence of the disease in women who have already been treated for it.

But, it was noticed back in the early 1980s that some women who were receiving the drug for cancer in one breast did not develop any tumorous growth in the other. This prompted the suggestion that Tamoxifen might have another preventative role for those women who are at risk of getting breast cancer but have yet to develop any signs of the disease.

Early Detection Of Breast Cancer Saves Lives

Significant progress in mammography technology continues to help physicians diagnose breast cancer in its earlier stages. When coupled with new treatment options, early diagnosis through mammography screening can significantly improve a woman’s chances of survival. That’s good news because in the United States more than 200,000 new cases of invasive breast cancer are diagnosed each year.

Mammography screening is the single most effective method of early detection. That’s why an annual mammogram is recommended for women over 40. A clinical breast examination by a health care professional should also be done on a regular basis. Additionally, women can take charge of their own breast health by understanding their personal risks of the disease, performing a breast self-exam every month and reporting any breast change promptly to their health care provider.

Unfortunately, studies have indicated that a significant number of women over 40 years of age fail to get a mammogram, and of those who do, many never follow up with a second mammogram. Women cite a number of reasons for their nonparticipation, including lack of finances and lack of time. It is important that women know that there are resources available to help address these issues. For example, throughout the year, low-cost or free mammography screening is available to many women who are over 40 and underinsured or uninsured. Additionally, many mammography centers offer extended hours and some even provide child care for moms having mammograms.

In an effort to encourage women to have an annual mammography screening, National Breast Cancer Awareness Month (NBCAM) sponsors recommend making every day National Mammography Day. Whether it means scheduling an appointment on a 40th birthday, or if it means reminding a friend to make an appointment, every step counts.

Can You Reduce Your Risk of Breast Cancer?

The more you understand about any subject, the more interesting it becomes. As you read this article you’ll find that the subject of cancer is certainly no exception.

We hear it all the time?lose weight for your health. Few people however, realize the extent to which this is critical to their physical well-being and ultimately their life expectancy.

In January 2003, the Journal of the American Medical Association featured a study finding that obesity appears to lessen life expectancy, especially among young adults. The researchers compared Body-Mass Index (BMI) to longevity and found a correlation between premature death and higher BMIs. For example, a 20-year-old white male, 5’10″ weighing 288 pounds with a BMI of greater than 40 was estimated to lose 13 years of his life as a result of obesity.Jamie McManus, M.D., F.A.A.F.P. and author of “Your Personal Guide to Wellness” notes that while this study referenced extreme levels of obesity, there are still millions of overweight people in developed countries with a life expectancy rate that is three to five years less than their healthy-weight counterparts. She also estimates that there are 600,000 obesity related deaths each year in America.

Just how does obesity shorten our lifespan? The answer to this question is complex, yet there is a clear link between obesity and the development of cancer. An extensive study conducted by the American Cancer Institute involving 750,000 people showed that obesity significantly increased the risk of cancer developing in the following organs: breast, colon, ovaries, uterus, pancreas, kidneys and gallbladder.

Michael Thun, MD, vice-president of epidemiology and surveillance research for the American Cancer Society (ACS) says one reason obesity may raise cancer risk is because fat cells produce a form of estrogen called estradiol that promotes rapid division of cells, increasing chances of a random genetic error while cells are replicating, which can lead to cancer. In addition, fat centered around the abdomen may increase insulin and insulin-like growth factors in the blood, which may increase cancer risk. “Women who are obese after menopause have a 50% higher relative risk of breast cancer,” notes Thun, “and obese men have a 40% higher relative risk of colon cancer?. Gallbladder and endometrial cancer risks are five times higher for obese individuals”.There is evidence that cancer rates in developed countries are increasing at 5 to 15 times faster than developing countries. A major contributor to this alarming reality has proven to be diet. In populations where the diet consists mostly of fresh fruit and vegetables and whole grains in contrast to the typical Western diet of fatty meats, refined flours, oils and sugars the risk of cancer is much lower. The interaction of diet and the development of cancer is an active field of research and Dr David Heber, M.D., Ph.D. and author of “What Color is Your Diet”, says “It appears that diet has its most significant effects after the cancer has already formed, acting to inhibit or stimulate the growth of that cancer”. At the risk of oversimplifying a complex set of interactions, the typical Western diet that leads to obesity may actually act to stimulate the growth of cancer cells.It is never too late to improve your health through healthful eating and adopting a more health-giving lifestyle. Here are simple steps to follow which can make an immediate improvement to your health and vitality.

The best time to learn about cancer is before you’re in the thick of things. Wise readers will keep reading to earn some valuable cancer experience while it’s still free.

1. Check your Body Mass Index (BMI) to determine if weight has become health risk. According to the Centers for Disease Control and Prevention, 60% of Americans are overweight, defined as having a BMI (a ratio of height to weight) over 25. Of those, nearly half (27%) qualify as obese, with a body mass index of 30 or more. In 1980, just 15% of Americans were considered obese. You can check your BMI at the website below.

2. Match your diet to your body’s requirements. If you eat and drink more calories than your body requires you will put on weight. Learn to control calories and portion sizes, make recipes leaner, and eat infrequently from fast food restaurants. Also learn how to snack with healthful choices.

3. Color your diet with a large variety of colorful, cancer-fighting fruit and vegetables. There are seven different color ranges of both fruit and vegetables and by choosing between 5 to 9 daily serves from a wide range of fruit and vegetables, we are extending our consumption of cancer (and other disease) fighting nutrients.

4. Eat lean protein with every meal. Protein provides a powerful signal to the brain providing a longer sense of fullness. The right source of protein is essential to controlling your hunger with fewer calories and necessary to maintain your lean muscle mass. Choices of protein should be flavored soy shakes with fruit; the white meat of chicken and turkey, seafood such as shrimps, prawns scallops and lobster and ocean fish or vegetarians may prefer soy based meat substitutes.

5. Rev up your metabolism with activity. If you want to enjoy a lifetime of well-being, exercise is a key ingredient. Colleen Doyle, MS, RD, director of nutrition and physical activity for the American Cancer Society (ACS), says adults should do something for 30 minutes each day that takes as much effort as a brisk walk. Children should be active for an hour each day. We are more likely to develop habits around things we enjoy, so seek activities which you enjoy doing. It is also helpful to build physical activity into your daily routine: use the stairs instead of the escalator or lift at work, park your car in the parking bay furthest from the super marketing and don’t use the remote control to change TV channels.

6. Get support to ensure you develop a healthful eating plan and reach your goal weight. Whilst a small percentage of people possess the discipline to lose weight, many obese people have developed strong thoughts and habits concerning the food they eat. In order to establish new habits, most people respond well to some form of consistent encouragement and coaching. A study, “Effects of Internet Behavioral Counseling on Weight Loss in Adults at Risk of Type 2 Diabetes” shows that participants who had the support of weight loss coaching lost more weight than those who didn’t. The study concluded that the support of a weight loss coach can significantly improve weight loss results. Being overweight or obese has been identified next to smoking, as the most preventable major risk to developing cancer. Even small weight losses have been shown to have beneficial health effects. So it’s never to late to start and you can never be too young or too old to be concerned about your health and do something about achieving a more healthy weight.

Now might be a good time to write down the main points covered above. The act of putting it down on paper will help you remember what’s important about cancer.

Breast Health: 8 Things Every Woman Needs To Know

I always advocate self-care as the first step in preventing and treating health challenges. When it comes to breast health, the importance of self-care is a message I can’t share often enough. It is great to see pink ribbons everywhere in October during National Breast Cancer Awareness Month! If I had my wish, every pink ribbon would carry an additional important message for women.

That message would read “You can improve your breast health and reduce the risk of breast cancer right now with a few simple lifestyle changes.”

We may not be able to control where we live or our genetic risk factors- it’s true. However, a growing body of research is showing us that women really can make a difference in their breast health through diet, exercise, and weight management.

These simple steps can help optimize your body’s hormonal balance and reduce the risk of developing breast cancer, and provide additional health, anti-aging, and disease-prevention benefits.

We need to emphasize that everyone should be focusing on what we can control not what we can’t.

- We can evaluate our hormone levels with a saliva test. The best way for premenopausal and postmenopausal women to know if their bodies have an imbalance of estrogen, progesterone and testosterone is to do a saliva test.
Saliva Testing is the most accurate and easy way to this.
We can use bio-identical hormones if we need hormone supplementation. Bio Identical means that the molecular structure of the hormones identically match the hormones made by our body as opposed to Pregnant Mare’s Urine which is natural to horses not humans.

We can change our habits: reduce alcohol consumption and quit smoking.

We can manage our weight and exercise daily. Studies also show that maintaining a healthy, average weight is just as important in favorably influencing the estrogen/progesterone ratio.
Regular exercise is equally important. On the other hand, obesity, high insulin levels, alcohol intake, smoking, oral contraceptives, hormones from meat and meat products, pesticides, and herbicides can swing this ratio in the wrong direction.

We can eat a balanced diet choosing Eat organic to avoid pesticides, herbicides, and estrogens in meat and dairy products. Include one to three servings of cruciferous vegetables like broccoli, bok choy, cauliflower, brussel sprouts, and cabbage in your diet each day.
Studies show that Indole 3 Carbinol the active ingredient helps balance estrogen levels.

We Can supplement wisely with EFA’s, essential fatty acids and use a fruit and vegetable concentrate if you do not eat 5 – 8 servings of fruits and vegetables daily.

We can do BSE’s breast self exams becoming more familiar with our own body

We can become better informed read Dr. John Lee’s “What Your Doctor May Not Tell You About Breast Cancer” as a start.

Breast Cancer and You; Risk Factors and Safety Precautions

Today’s woman is more knowledgeable and conscientious than ever about the risks of breast cancer. This is especially true for women over 40 years of age, who have crossed the threshold of increased risk of breast cancer.

Age is so important to the development of breast cancer that about 76% of women who develop it have no other risk factors other than age. However, all women, regardless of age or race, need to acknowledge the risk of developing it. All women are at risk.

Women who have never smoked a day in their entire lives can develop breast cancer. Women who have been always been health conscious can also develop it. In fact, nearly one woman out of eleven will experience breast cancer. A staggering statistic by anybody’s standards!

An estimated 211,000 new cases of breast cancer was diagnosed this past year. Even with the increased awareness programs, early detection through annual mammography screening and instruction for self-examination, breast cancer remains a leading cause of death for women.

Breast cancer, like other forms of cancer, is a disease of the cells. In all, there are about fifteen different types of breast cancer. Some are more serious than others, but the one common factor each shares is that neither the cause nor the cure has been found.

There are four recognized developmental stages of breast cancer: (1.) State 0: Cancer cells are present in either the lining of the milk glands (lobules), or in the tubes (ducts) that link the milk glands to the nipple. No cancer cells have spread to the nearby fatty tissue.
(2.) Stage 1: Cancer has spread to nearby fatty tissue in the breast. Tumor size is about 1” or under; no cancer cells are present in surrounding lymph nodes.
(3.) Stage 2: Size of tumor is 1” to 2” in diameter; cancer cells may have also spread to nearby lymph nodes.
(4.) Stage 3: Cancer is locally advanced. Tumors are approximately 2” or larger in diameter, or tumors of any size have spread to lymph nodes under the arm or in the chest (above or below the collarbone).
(5.) Stage 4: Metastatic, advanced breast cancer. The cancer has spread from the breast and lymph nodes to other parts of the body.

Early detection of breast cancer remains a woman’s best chance of survival, and women of all ages should take advantage of all the resources available.

Every woman should:

1.) Become educated about the risk factors associated with breast cancer.
2.) Become knowledgeable about the types, stages, and symptoms of breast cancer.
3.) Learn the correct procedure for self-examination tests, and perform them routinely.

Long-term use of oral contraceptives, early menstruation, late first full-term pregnancy, exposure to high doses of radiation – puberty through childbearing years, and inherited genetic mutation can all increase a woman’s risk of acquiring breast cancer.

Women 40 years of age and older should also:

1.) Have an annual mammography screening.
2.) Become educated about increased age-related risks associated with breast cancer.

Recent studies confirm that risk of breast cancer in midlife increases with regular consumption of alcohol, hormone replacement therapy, weight, and body mass distribution.

During self-examination, look for a lump or thickening in the breast, a discharge from the nipple, scaliness on the skin or around the nipple, a change in shape, color, or texture, and dimpling or puckering.

If you detect a lump, don’t panic. About 85-percent of all lumps turn out to be nonmalignant. Make an appointment with your doctor for a more thorough examination, and tests.

Treatment for breast cancer today is often less radical than in years past, and chances for survival much better when the tumor is discovered early.

Breast Cancer and You; Risk Factors and Safety Precautions

Today’s woman is more knowledgeable and conscientious than ever about the risks of breast cancer. This is especially true for women over 40 years of age, who have crossed the threshold of increased risk of breast cancer.

Age is so important to the development of breast cancer that about 76% of women who develop it have no other risk factors other than age. However, all women, regardless of age or race, need to acknowledge the risk of developing it. All women are at risk.

Women who have never smoked a day in their entire lives can develop breast cancer. Women who have been always been health conscious can also develop it. In fact, nearly one woman out of eleven will experience breast cancer. A staggering statistic by anybody’s standards!

An estimated 211,000 new cases of breast cancer was diagnosed this past year. Even with the increased awareness programs, early detection through annual mammography screening and instruction for self-examination, breast cancer remains a leading cause of death for women.

Breast cancer, like other forms of cancer, is a disease of the cells. In all, there are about fifteen different types of breast cancer. Some are more serious than others, but the one common factor each shares is that neither the cause nor the cure has been found.

There are four recognized developmental stages of breast cancer: (1.) State 0: Cancer cells are present in either the lining of the milk glands (lobules), or in the tubes (ducts) that link the milk glands to the nipple. No cancer cells have spread to the nearby fatty tissue.
(2.) Stage 1: Cancer has spread to nearby fatty tissue in the breast. Tumor size is about 1” or under; no cancer cells are present in surrounding lymph nodes.
(3.) Stage 2: Size of tumor is 1” to 2” in diameter; cancer cells may have also spread to nearby lymph nodes.
(4.) Stage 3: Cancer is locally advanced. Tumors are approximately 2” or larger in diameter, or tumors of any size have spread to lymph nodes under the arm or in the chest (above or below the collarbone).
(5.) Stage 4: Metastatic, advanced breast cancer. The cancer has spread from the breast and lymph nodes to other parts of the body.

Early detection of breast cancer remains a woman’s best chance of survival, and women of all ages should take advantage of all the resources available.

Every woman should:

1.) Become educated about the risk factors associated with breast cancer.
2.) Become knowledgeable about the types, stages, and symptoms of breast cancer.
3.) Learn the correct procedure for self-examination tests, and perform them routinely.

Long-term use of oral contraceptives, early menstruation, late first full-term pregnancy, exposure to high doses of radiation – puberty through childbearing years, and inherited genetic mutation can all increase a woman’s risk of acquiring breast cancer.

Women 40 years of age and older should also:

1.) Have an annual mammography screening.
2.) Become educated about increased age-related risks associated with breast cancer.

Recent studies confirm that risk of breast cancer in midlife increases with regular consumption of alcohol, hormone replacement therapy, weight, and body mass distribution.

During self-examination, look for a lump or thickening in the breast, a discharge from the nipple, scaliness on the skin or around the nipple, a change in shape, color, or texture, and dimpling or puckering.

If you detect a lump, don’t panic. About 85-percent of all lumps turn out to be nonmalignant. Make an appointment with your doctor for a more thorough examination, and tests.

Treatment for breast cancer today is often less radical than in years past, and chances for survival much better when the tumor is discovered early.